Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CB-128 | CB-128 | Italy | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT| 3TC| DDI| DDC| D4T| IDV| RTV|RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82S | L33F, T74P | I13V, N37D, L63P, C67Y, H69K, A71V, V77I |
| >CB-128| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVFEEMDLPGRWKPKMIGGIGGFVKVRQYD QIPIEIYGKKVIGPVLIGPTPSNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML | D67DA | K103N, G190A | T27TS, T39S, R83K, T107TP, D237E |
| >CB-128| codons 1-242 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALVEICSELEKEGKISKIGPENPYNTPV FAIKKKASTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKNKSVPVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPEKWT VQ |
References
| Author | Title | Citation |
| Balotta, C | Prevalence of multiple dideoxynucleoside analogue resistance (MddNR) in a multicenter cohort of HIV-1 infected Italian patients with virologic failure. | JAIDS, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |