<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179E A33AT, V35T, T39A, K43KR, V60I, I135V, I142IV, K173I, Q174K, D177E, T200A, Q207G, R211K, V245Q, E248D, D250E, A272P, K277R, Q278H, T286A, V292I, I293V, E297A, K311R, D324E, I329V, G333E, Q334L  
>HJ126| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKTLTEICAEMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIEI
YQYMDDLYVGSDLEIGQHRAKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGAKALTEIVPLTAEAE
LELAENREILREPVHGVYYDPSKELIAEVQKQELGQWTYQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L5LF, I13V, K14KR, K20I, E35D, M36I, P39Q, R41K, H69K, V82VI, L89M  
>HJ126| codons 1-99
PQITFWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Aghokeng, AF Scale-up of antiretroviral treatment in sub-Saharan Africa is accompanied by increasing HIV-1 drug resistance mutations in drug-naive patients. AIDS, 2011