<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, L74V, L210W D67G, T215C, K219R L100I, K103N, Y181YC V108VI K43Q, E44D, V60I, S68SG, V111I, V118VI, K122E, D123DN, I135T, G196E, E203K, Q207E, H208Y, R211K, F214FL, K223Q, P243T, V245K, D250E, A272P, I293V, M357S, R358K, A376C, T377N, I382IT, K390R  
>13578A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPI
FAIKKKGGDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTILDIGDAYFSIPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVGSDLEIEQHRTKIKELREYLWKWGLCTPDRKHQQEPPFLWMGYELHPDKWT
VQTIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARSKGA
HTNDVKQLTEAVQKICNESIVTWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I54V, L76V, I84V, L90M L10F, L33F, K43T I13V, K20R, E35D, M36I, R41RK, K55KR, D60E, L63P, I64V, L89I  
>13578A| codons 1-99
PQITLWQRPFVTVKIGGQLREALLDTGADDTIFEDINLPGKWTPKIIGGIGGFVRVRQYE
QIPVEICGHKAIGTVVVGPTPVNVIGRNIMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010