<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115YF, M184V       K49E, V90I, E138EG, I142K, K166R, F214L, V245E, D250E, K277R, I293V, V317A, G333E, G335GS, M357KT, A360AV, T369TA, A376S, T377K, T386I, K390R  
>13514A| codons 2-399
ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISEIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAFFSVPLD
KDFRKYTAFTIPSINNGTPGKRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVIY
QYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTEEAEL
ELAENREILKEPVHGAYYDPSKDLIAEIQKQEQSQWTYQIYQEPFKNLKTGKYARTRGVH
TNDVKQLAEAVQKISKESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54L, V82A, L90M L10F, V11VI, L33F I13V, K20R, M36L, N37D, I62V, L63P, K70KT, A71V, L89LIM, I93L  
>13514A| codons 1-99
PQITLWQRPFITVKIGGQLREALLDTGADDTVFEELDLPGRWKPKLIGGIGGFLKVRQYD
QVPIEICGHTVIGTVLVGPTPANIIGRNMMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010