<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, L210W, T215Y K219KN K103N, Y188L   V35E, T39A, S68G, A98S, K102N, V118I, K122E, T139K, I142V, S162C, K173N, Q174K, E194ED, G196K, T200KQ, I202V, Q207E, R211K, L228LH, S251C, A272P, K277KR, Q278H, D324E, Q334L, G359S, I375V, T386I, E399D, A400AT  
>13335A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKNNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNEKPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRNKNPDIVI
YQYVDDLLVGSDLDIKQHRQKVEELREHLWKWGFYTPDNKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDCWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEAVQKVATESIVIWGKIPKFKLPIQKETWDT

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, I84V, L90M L10F, L33F, T74P I13V, K20R, E35D, M36I, N37DE, L63P, A71V, I72V, I93L  
>13335A| codons 1-99
PQITLWQRPFVTVKIGGQLREALLDTGADDTVFEDIELPGRWKPKLIGGIGGFVKVRQYD
QIPIEICGHKVVGPVLVGPTPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010