<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, M184V, L210W, T215Y D67G, K219KR K103N   T27S, T39TA, E44D, S48E, V60I, K101Q, V118I, I142V, D177N, I178M, V179I, L193M, G196E, T200A, R211KT, L228HP, K238KR, T286TA, I293V, E297K, I329L, G333E, Q334H, M357T, T369V, A376S, S379C, K390KR  
>12740A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALVEICAELEKDGKIEKIGPENPYNTPI
FAIKKKGSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKNKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNMII
YQYVDDLYVGSDMEIEQHRAKIEELRQHLWTWGFYTPDRKHQKEPPFPWMGYELHPDRWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQEHGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLVEAVQKISTECIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54L, V82T, L90M V11VI, G73S L10I, I15V, L19V, K20KR, E35D, M36MI, N37D, K55KR, I62V, L63P, A71T, I72T, I85V, I93L, C95F  
>12740A| codons 1-99
PQITLWQRPIITIKVGGQVREALLDTGADDTVLEDIDLPGRWKPKLIGGIGGFLRVRQYD
QVPIEICGHKTTSTVLVGPTPTNIVGRNLMTQLGFTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010