<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54IL, L90M L10F, N88G I15V, L19I, K20T, E35DG, M36I, R41RK, Q61E, I62V, L63P, A71IT, V77VL, P79PS  
>12177A| codons 1-99
PQITLWQRPFVTIKVGGQITEALLDTGADDTILEGINLPGKWKPKIVGGIGGFLKVRQYD
EVPIEICGHKTIGTVLLGSTPVNIIGRGLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y       K20R, K43Q, E44D, V118I, K122E, K166KR, G196E, T200A, E203V, Q207E, H208F, R211RK, V245E, E248Q, D250E, K277R, Q278H, I293V, I329IL, K347KQ, K350KR, G359GS, A360T, K366KR, T369V, A376T, K390KR  
>12177A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRAKIVELREFLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPQKESWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFQNLRTGKYARMRST
HTNDVRQLVEAVQKITTESIVIWGKTPKFRLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010