Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12070A | 12070A | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46IV, I47V, I54M, V82A | L10F, L33F | M36MI, K55KR, R57RK, L63P, A71V, I72V |
| >12070A| codons 1-99 PQITLWQRPFVTIKIGGQLKEALLDTGADDTIFEEINLPGRWKPKVVGGIGGFMRVKQYD QIPIEICGHKVVGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, M184V, L210LW, T215F | Y181C, G190A | A98G, V108VI, V179VD | K43KE, R83RK, V90I, K122E, D123E, S162Y, E203D, V245M, D250E, A272P, K277R, I293IV, E297K, D324E, I329L, G335GD, R356K, R358RK, V365I, K366KR, A376S, T386I, A400T |
| >12070A| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKIVDFRELNKKTQDFWEIQLGIPHPGGLKKKKSVTILDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIDI CQYVDDLYVASDLEIGQHRTKIDELRQHLWRWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKELIAELQKQGQDQWTYQIYQEPFKNLKTGKYAKMKGA HTNDIRQLTEAVQKISTESIVIWGKIPKFKLPIQKETWET |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |