<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46IV, I47V, I54M, V82A L10F, L33F M36MI, K55KR, R57RK, L63P, A71V, I72V  
>12070A| codons 1-99
PQITLWQRPFVTIKIGGQLKEALLDTGADDTIFEEINLPGRWKPKVVGGIGGFMRVKQYD
QIPIEICGHKVVGTVLVGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, L210LW, T215F   Y181C, G190A A98G, V108VI, V179VD K43KE, R83RK, V90I, K122E, D123E, S162Y, E203D, V245M, D250E, A272P, K277R, I293IV, E297K, D324E, I329L, G335GD, R356K, R358RK, V365I, K366KR, A376S, T386I  
>12070A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKIVDFRELNKKTQDFWEIQLGIPHPGGLKKKKSVTILDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIDI
CQYVDDLYVASDLEIGQHRTKIDELRQHLWRWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKELIAELQKQGQDQWTYQIYQEPFKNLKTGKYAKMKGA
HTNDIRQLTEAVQKISTESIVIWGKIPKFKLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010