<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70KR, M184V, L210W, T215Y V75M, K219Q K103KN, G190A A98G K20R, T39K, K43E, V60I, K82R, R83K, V118I, D123E, R172K, D177E, G196D, T200E, E203K, R211KT, K223Q, L228H, A272P, K277R, E291D, I293V, E297A, G335GS, K366R, S379SC, K390KR  
>12025A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICKELEEEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLMDFRELNRKTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPEIVI
YQYVDDLYVASDLEIDQHREKIKELRQHLWTWGFYTPDQKHQQEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQSQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVRQLTEAVQKIATECIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54L, V82A L24I, L33F, G73CS, T74TP L10I, I13IV, E35ED, R41K, K55R, R57K, I62IV, L63P, C67CY, A71V, V77VI  
>12025A| codons 1-99
PQITLWQRPIVTVKIGGQLKEALIDTGADDTVFEDMNLPGKWKPKLIGGIGGFLRVKQYD
QVPIEIYGHKVISPVLIGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010