<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S L10F, L89V I13V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, T74S  
>11741A| codons 1-99
PQITLWQRPFVTVKIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVPIEICGKKAIGSVLVGPTPVNIIGRSVLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69DN, K70R, M184MV D67DG, V75VIM, T215TI, K219Q L100I, K103N   E6D, V8VI, K20R, V35T, T39A, V60I, K122E, D123S, I135T, K173S, Q174K, D177EG, V179I, T200A, Q207A, R211S, F214L, D218E, L228HR, V245Q, E248D, D250E, T286A, E291D, I293V, P294T, E297K, G335D, M357R, G359S, A371V, I375V, A376V, T377M, T386A  
>11741A| codons 1-399
PISPIDTIPVKLKPGMDGPRVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPI
FAIKKKGSNRWRKLMDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPGIII
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGLITPEQKHQKEPPFRWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARRRSA
HTNDVKQLTEVVQKVVMESIVIWGKAPKFKLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010