<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54M, L76V, V82F L33F, K43T L10I, I13V, E35D, M36V, D60E, L63P, E65D, H69HY, A71V, I72V, L89LM, I93L  
>11486A| codons 1-99
PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEDVNLPGRWTPKIIGGIGGFMKVRQYE
QIPIDICGYKVVGTVVVGPTPFNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70KR, L74I, M184V, T215Y   K103N V108VI E44D, V111I, D123E, K173T, Q174K, E203ED, Q207E, H208Y, R211K, V245M, E248DN, D250E, A272P, K277R, I293V, E297K, G333E, Q334N, G335S, K350KR, M357MV, G359GS, A360T, T369TA, A371V, A376T, T386IM, K390R, E399D  
>11486A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV
FAIKKKNSDRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDIGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI
YQYVDDLYVGSDLEIGQHRTKIDELREYLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPNKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQENSQWTYQIYQEPFKNLRTGKYARVRST
HTNDVKQLAEVVQKITTESIVIWGKMPKFRLPIQKETWD

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010