<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V, T215FL K219E K101E, Y181I, G190S   P4S, V8VI, K20KR, K64R, T69TN, I135L, K173N, R211K, L228R, V245E, D250E, I257L, T286A, V292I, I293V, E297Q, T338S, G359S, A376S, K385R, T386I, K390R  
>11435A| codons 1-399
PISSIETIPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIRKKNSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRNQNPDIVI
IQYVDDLYVSSDLEIGQHRTKIEELRQHLLKWGFLTPDEKHQKEPPFRWMGYELHPDKWT
VQPIELPEKESWTVNDLQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEIVPLTQEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWSYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEAVQKISTESIVIWGRIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84IV, L90LM G73GAST L10I, T12S, I13V, L19I, I62IV, L63P, H69QR, A71AV, V77I  
>11435A| codons 1-99
PQITLWQRPIVSVKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGRKVITTVLIGPTPVNVIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010