Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215Y | K103N, Y181I | K20R, V35M, K43Q, V118I, K122KE, I135T, K166R, V179VI, Q207E, R211K, V245I, K277R, T286A, I293V, E297A, G335D, R356K, G359S, T369V, T386I, K390R |
| >11269A| codons 1-399 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTELEQEGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIII IQYMDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIILPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLVEAVQKIATESIVIWGKIPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L33LF, G73S | L10I, I15V, G16W, L19Q, K20M, K55R, R57K, I62V, L63P, H69Q, A71V, I72L, I93L |
| >11269A| codons 1-99 PQITLWQRPIVTIKVWGQQMEALLDTGADDTVFEEMNLPGRWKPKLIGGIGGFVRVKQYD QVPIEICGQKVLSTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |