<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M L33LF, G73S L10I, I15V, G16W, L19Q, K20M, K55R, R57K, I62V, L63P, H69Q, A71V, I72L, I93L  
>11269A| codons 1-99
PQITLWQRPIVTIKVWGQQMEALLDTGADDTVFEEMNLPGRWKPKLIGGIGGFVRVKQYD
QVPIEICGQKVLSTVLVGPTPANIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L210W, T215Y   K103N, Y181I   K20R, V35M, K43Q, V118I, K122KE, I135T, K166R, V179VI, Q207E, R211K, V245I, K277R, T286A, I293V, E297A, G335D, R356K, G359S, T369V, T386I, K390R  
>11269A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTELEQEGKISKIGPENPYNTPV
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIII
IQYMDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIILPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLVEAVQKIATESIVIWGKIPKFRLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010