<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y N348I Y188L   V35L, T39A, K43E, E44ED, V60I, V118I, K122E, D123E, K173R, Q174K, V179VI, V189VI, Q207K, R211D, D218DE, A272P, K281R, I293IV, E297K, D324E, I329IL, G333DE, Q334QH, R356RK, G359GS, A360AV, T386TI  
>11057A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICAELEEDGKISKIGPENPYNTPI
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPDIII
YQYVDDLLIGSDLEIGQHRTKIEELRKHLWDWGFYTPEKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKELIAELQKQEHGQWTYQIYQEPFKILKTGKYAKMRSV
HTNDVKQLTEAVQKIATESIVIWGKIPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47IV, I54L, I84V, L90M L10F, L33F, T74P I13V, E35ED, M36L, K55KR, I62V, L63P, A71V, I72IM  
>11057A| codons 1-99
PQITLWQRPFVTVKIGGQLKEALLDTGADDTIFEDLNLPGRWKPKMVGGIGGFLRVRQYD
QVPIEICGHKVMGPVLVGPTPVNVIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010