<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54A, V82A, L90M L33F, K43T L10I, V11VL, I13V, K14KR, I15V, K20R, E34N, E35D, M36I, P39S, R41K, D60E, I62V, L63P, I64V, H69Y, A71V, Q92K, I93L  
>11025A| codons 1-99
PQITLWQRPILTVRVGGQLREALLDTGADDTVFNDINLSGKWTPKMIGGIGGFAKVRQYE
QVPVEICGYKVIGTVLVGPTPANIIGRNLMTKLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y V75LM, F77L K103N Y318F V35L, T39K, E40F, K43E, V118I, K122E, I135M, E138Q, T200TAEK, Q207DE, R211K, Q278H, A288S, I293V, E297A, D324DE, N348T, M357T, T386I, K390R  
>11025A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICKFLEEEGKISKIGPENPYNTPV
FAIKKKNSTKWRKLMDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSMNNQTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRKKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGTKSLTEVVPLTAEAE
LELAENREILKEPVHGVFYDPSKELIAEIQKQGQGQWTYQIYQEPFKTLKTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010