<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47IV, I54V, V82A   L10I, K20R, E35D, M36I, K43I, K55R, I62V, L63P, I64IV, A71V, I72V  
>10983A| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTILEDINLPGRWIPKIVGGIGGFVRVRQYD
QVPVEICGHKVVGTVLVGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219R   V108I, F227FL K20R, K22R, E40F, K43E, T107TA, V118I, K122E, S162SDGN, T200E, I202V, E203K, H208Y, K223E, L228H, T286A, V317A, K323KT, Q334E, G359S, K390R, E399D  
>10983A| codons 1-399
PISPIETVPVKLKPGMDGPRVRQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVAILDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHREKVKELRQYLWRWGFYTPDRKHQEEPPLHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKEPVHGAYYDPSTDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWD

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010