<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, T215Y V75A, K219N L100I, K103N   P9PS, K20R, V35M, K43E, E44D, I47L, K73M, K102Q, V118I, K122KE, D123DE, S162D, D177E, G196E, E203Q, L210S, R211K, D218E, I293V, P294Q, I329V, R356K, G359S, A371V, A376S, K390R, K395R, E399D  
>10741A| codons 1-400
PISPIETVSVKLKPGMDGPRVKQWPLTEEKIKALMEICTELEEDGKLSKIGPENPYNTPV
FAIKKKNSTKWRMVADFRELNKRTQDFWEVQLGIPHPAGIKQNKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIEQHRTKIQELRQHLSKWGFYTPENKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVQLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEVVQKISTESIVIWGKTPKFRLPIQRETWDA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82ST K43KT E35D, M36I, R57K, I62V, L63P, I64V, A71V, T74S, V77VI, I93IL  
>10741A| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGRWTPKMIGGIGGFVKVKQYD
QVPVEICGHKVIGSVLIGPTPTNIIGRNLLTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010