<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46ML, I54IATV, V82VA L24LI, K43KT L10I, K20M, E35EG, M36MI, R41K, D60E, Q61QH, I62V, L63PS, I64V, A71AV, V77VI, I93L  
>10643A| codons 1-99
PQITLWQRPIVTIKIGGQLMEALIDTGADDTVLEGINLPGKWTPKLIGGIGGFVKVRQYE
HVSVEICGHKVIGTVLIGPTPANIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67N, K70R, L74V, M184MIV, L210W, T215F K219Q K101HPQ, G190GA   T39A, V118VI, K122KE, Q174K, D177DE, I178IM, Q207E, H208HY, R211K, D218DE, L228LH, Q242QH, A272AP, A288S, I293V, E297A, V317G, Q334L, M357MIR, R358K, G359S, A371V, I375IV, A376V, S379C, T386TA, K390R V111VIM
>10643A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDMGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPEMVI
YQYVDDLYVASDLEIGQHRTKIEELREYLWKWGFFTPEQKHQKEPPFHWMGYELHPDKWT
VHPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSLTEVVPLTAEAE
LELAENREILKEPVHGGYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARRKSA
HTNDVKQLTEVVQKVVTECIVIWGKAPKFRLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010