<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, I84V L24I, L33F L10I, T12P, I13V, K14R, L19LI, M36I, N37D, L63P, I64M, A71V, P79AD, N83S, I93L  
>10626A| codons 1-99
PQITLWQRPIVPVRIGGQIKEALIDTGADDTVFEEIDLPGRWKPKMIGGIGGFVKVRQYD
QIPMEICGHKVIGTVLVGDTPVSVIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69DE, K70R, T215F D67G, K219Q K101P, K103NS   K20R, K22KR, S68G, K104KR, V118I, I135T, K173KQ, T200I, F214L, L228K, A288AS, I293V, E297A, V317A, G359S, A371T, A376T, T386M, E399D  
>10626A| codons 1-399
PISPIETVPVKLKPGMDGPRVRQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKGGERWRKLVDFRELNKRTQDFWEVQLGIPHPAGLPKSRSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRQQNPDIVI
YQYMDDLYVGSDLEIGQHRIKIEELRQHLLRWGLFTPDQKHQKEPPFKWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVVPLTAEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTETVQKITTESIVIWGKMPKFKLPIQKETWD

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010