<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, M184V T215V, K219Q K101KE, G190A   V35M, E36ED, V60I, R83RK, K122E, E138A, V179I, I202V, R211K, F214FL, D237E, A272P, K277R, I293V, P294PS, E297EK, D324DE, R356K, A360AV, A376S G359GRS
>10546A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMDICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSDRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII
YQYVDDLYVASDLEIGQHRTKVEELRQHLLKWGLVTPDQKHQKEPPFLWMGYELHPEKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVSLTKEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSV
HTNDVKQLTEAVQKISTESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, V82A, L90M L33F, L89V L10I, I13V, L19I, K20R, E35D, M36I, N37E, I62V, L63P, I66F, K70R, A71V, I72T, Q92K  
>10546A| codons 1-99
PQITLWQRPIVTVKIGGQIREALLDTGADDTVFEDIELPGRWKPKIIGGVGGFVKVRQYD
QVPIEFCGHRVTGTVLVGPTPANIIGRNVMTKIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010