<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, L210W, T215Y K219KN, N348I L100I, K103N   K20KR, V35M, V118VI, K122E, S162SAGT, K173T, T200TI, Q207E, R211K, E224ED, P243S, V245T, A272P, K277R, L283LI, T286A, E297K, M357V, A360T, A376T, T377R, T386A, K390R, Q394T, E399D  
>10498A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQTSMTKILEPFRTQNPDIVI
YQYVDDLYVGSDLEIGQHRIKIEELREHLWKWGFYTPDNKHQKDPPFLWMGYELHPDKWT
VQSITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGAKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYARVRGT
HTNDVKQLTEAVQKITRESIVIWGKAPKFRLPITKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82C, I84V K43KT L10I, I13V, L19I, K20R, E35D, M36I, N37D, R41RK, D60E, Q61E, L63P, A71AV, L89LM, I93L  
>10498A| codons 1-99
PQITLWQRPIVTVKIGGQIREALLDTGADDTVLEDIDLPGKWTPKMIGGIGGFVKVRQYE
EIPIEICGHKVIGTVLVGPTPCNVIGRNMLTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010