<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y A62V, V75I, K219N K101E, G190E E138K W88C, V118I, K122E, I135V, S162ST, Q174R, D177N, V179G, G196E, K223Q, L228HR, V245E, A272P, K277R, E291D, I293V, E297K, M357T, V365I, T386TI, K390KR, K395KR, E399EG  
>10413A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FVIKKKNSTKWRKLIDFRELNKRTQDFCEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSVNNKTPGIRYQYNVLPQGWKGSPAIFQTSMTKILEPFRKRNPNIGI
YQYMDDLYVESDLEIEQHRTKIEELRQHLWRWGFYTPDNKHQQEPPFRWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDIKQLTEAVQKIATESIVIWGKIPKFRLPIQRETWGA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L10F, L33F, G73T I13V, K20T, M36I, L63P, I93L, C95F  
>10413A| codons 1-99
PQITLWQRPFVTVKIGGQLTEALLDTGADDTVFEEINLPGRWKPKIIGGIGGFVKVRQYD
QIPIEICGHKAITTVLVGPTPVNVIGRNLMTQLGFTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010