<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, M184V, L210W, T215Y K219N, N348I L100I, K103N   T7TP, K20R, V35I, K43E, E44A, V118I, K122P, D123E, I142V, S162N, K166R, D177E, I178L, V179IT, V189VI, G196E, T200A, E203D, L205F, H208Y, R211K, L228H, E248D, A272S, A288S, I293V, Q334E, P345Q, V365I, S379C, T386I, K390R  
>10256A| codons 1-399
PISPIEPVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEEAGKISKIGPENPYNTPV
FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL
DPEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQNSMTRILEPFRKQNPELTI
YQYVDDLYIGSDLEIEQHRAKIDEFRQYLWKWGFYTPDNKHQKEPPFHWMGYELHPDKWT
VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKSLTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEQFKILKTGKYARMRGA
HTNDIKQLTEAVQKIATECIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L89V L10I, I15V, K20I, E35D, M36I, N37D, L63P, I64IM, H69Q, A71V, I72IV, I85V, Q92QL, I93M T91TCS
>10256A| codons 1-99
PQITLWQRPIVTIKVGGQLIEALLDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVRQYD
QIPMEICGQKVVGTVLVGPTPVNVVGRNVMSLMGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010