<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, L74I, M184V, T215F K219Q, N348I L100I, K103N   V35I, K122E, D123E, I135V, S162SN, D177E, I178IM, Q197E, R211RK, D218DE, L228H, V245M, A272P, K281R, I293V, E297EA, D324DE, M357MT, V365I, A376S, E399G P243K
>10153A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNSDRWRKIVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPEMVI
YQYVDDLYVGSDLEIGEHRTKIEELRQHLLKWGFFTPEQKHQKEPPFHWMGYELHPDKWT
VQKIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVVPLTAEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKILKTGKYARTRGA
HTNDIKQLTEAVQKISTESIVIWGKTPKFKLPIQKETWGA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54M, I84V L10F, L89V I13V, L19LP, K20V, M36I, L63P, A71V, T74S  
>10153A| codons 1-99
PQITLWQRPFVTVKIGGQPVEALLDTGADDTILEEINLPGRWKPKIVGGIGGFMKVRQYD
QIPIEICGHKVIGSVLVGPTPVNVIGRNVLTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010