<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69DN, K70R, T215F K219Q     K20R, T39E, V60I, K64H, A98S, V118I, K122E, D123DN, I135T, S162SDGN, T200A, F214L, D218E, L228H, A288S, M357T, R358K  
>10017A| codons 2-399
ISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICEEMEKEGKISKIGPENPYNTPIF
AIHKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPLD
ENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGLFTPEQKHQKEPPFHWMGYELHPDKWTV
QPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVIPLTEEAEL
ELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTKGAH
TNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54L, V82A, L90M L33F, K43T, G73S T4S, L10V, I13IV, I15V, G16A, L24F, I62V, L63P, A71I, I72R, V77VI, I93L  
>10017A| codons 1-99
PQISLWQRPVVTVKVAGQLKEALFDTGADDTVFEEMNLPGRWTPKIIGGIGGFLKVRQYD
QVPIEICGHKIRSTVLIGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010