<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219R K103KN V108I, F227L, K238KN K20KR, K22KR, E40F, K43E, T107TA, V118I, K122E, S162SG, T200E, I202IV, E203K, H208Y, K223E, L228H, T286A, V317A, Q334E, R356RK, G359S, K390R, E399ED  
>09875A| codons 1-399
PISPIETVPVKLKPGMDGPRVRQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVAILDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQGSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHREKVKELRQYLWRWGFYTPDRKHQEEPPLHWMGYELHPDNWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47IV, I54V, V82A, L90LM L33LI L10I, K20R, E35D, M36I, K43I, K55R, I62V, L63P, I64IV, A71V, I72V  
>09875A| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTIIEDINLPGRWIPKIVGGIGGFVRVRQYD
QVPVEICGHKVVGTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010