<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75T, N348I Y181C V108VI V35M, S68G, T69S, A98S, K101Q, V106I, D121H, I135R, T139M, S162D, K173R, Q174K, D177E, F214L, D218DE, A272P, K277KR, T286A, I293V, G333E, Q334H, G335S, R356K, K390KR  
>09872A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGSKWRKLTDFRELNKRTQDFWEVQLGIPHPSGLQKKKSITILDVGDAYFSVPL
HKDFRKYTAFTIPSRNNEMPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRRKNPEIVI
CQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPEKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEHSQWTYQIYQEPFKILKTGKYAKMRGA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L63A, K70KR, A71AT, I72EV, V77I, I93L  
>09872A| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIAIEICGHRTVGTVLIGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010