<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, I84V Q58E L10I, K20R, E35D, M36I, N37E, I62V, L63P, A71T, I93L  
>09759A| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIELPGRWKPKIIGGIGGFVKVREYD
QVPIEICGHKTIGTVVVGPTPVNVIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F, Q151M V75I, F77L, F116Y Y181C   V35I, I50V, S68G, V118I, K122E, I135V, T139TA, R172K, Q174QR, I202V, R211K, F214L, A272P, L283I, I293V, E297R, L301I, I326V, Q334E, Y339F, A371V, I375V, T377R, S379C, K390R  
>09759A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKVGPENPYNTPV
FAIKRKDGTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFYSIPL
DEDFRKYTAFTIPSVNNEAPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFKKRNPDIVI
CQYMDDLYVGSDLEIGQHRTKVEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVVPLTREAE
IELAENREILKEPVHGVYYDPSKDLVAEIQKQGEGQWTFQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEVVQKVARECIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010