<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, M184V, L210W, T215Y D67G, K70T, V75A, K219E, N348I K101E, Y181C, G190A V108I, V179F V35IT, T39A, E40ED, E44D, V60I, S68R, K103R, V118I, K122E, K166KR, R172K, Q174R, D177N, G196E, T200I, H221Y, A272P, L283I, A288S, E297K, A327V, I341F, A371V, I375T, T386I, K390R  
>09705A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICADLEKDGKISKIGPENPYNTPI
FAIKKKGRDTWRKLADFRELNKRTQDFWEVQLGIPHPAGLEKRKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFKKRNPNIFI
CQYVDDLYVASDLEIEQHRIKIEELRQHLWRWGFYTPDEKYQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKSLTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIVEIQKQGQGQWTYQFYQEPFKILKTGKYARMRGA
HTNDVKQLTEVVQKTATESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82AT, I84V, L90M L33F, F53L, L89V L10I, I13V, I15V, K20T, E35D, M36I, N37D, K55R, D60E, I62V, L63P, I66F, K70E, A71V, Q92K  
>09705A| codons 1-99
PQITLWQRPIVTVKVGGQLTEALLDTGADDTVFEDIDLPGRWKPKLIGGIGGLVRVRQYE
QVPIEFCGHEVIGTVLVGPTPTNVIGRNVMTKIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010