<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54LV, V82VF, I84IV F53FL L10I, L19Q, K43KQ, L63T, C67W, I72T, V77I  
>09655A| codons 1-99
PQITLWQRPIVTIKIGGQQKEALLDTGADDTVLEEMNLPGRWQPKIIGGIGGLVKVRQYD
QITIEIWGHKATGTVLIGPTPFNVIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W A62AV, V75L, T215C K103N V108VI E44D, V118I, K173R, E203K, H208Y, R211K, K223Q, Y271YF, T286A, V292I, E297A, S322A, G333E, G359S, Q367L, A371V, A400S  
>09655A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV
FVIKKKNSDKWRKLLDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSIPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIKELRQYLWKWGFCTPDKKHQQEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIFAGIKVKQLCKLLRGAKALTEIIPLTAEAE
LELAENREILKEPVHGVYYDPAKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKLLTEVVQKIATESIVIWGKTPKFKLPIQKETWES

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010