<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V, L90M L10F, Q58E I15V, K20R, M36I, R57K, D60E, I62V, L63P, A71V, I85V, Q92K  
>09316A| codons 1-99
PQITLWQRPFVTIKVGGQLREALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVKEYE
QVPIEICGHKVIGTVLVGPTPTNVVGRNLMTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, Y115F, M184V, L210W, T215Y   Y181C, G190A A98G, V108I K32KR, W88S, K101Q, V118I, D121H, K122E, I135L, T165I, D177E, I178L, G196K, H221Y, A272P, K277R, T286A, A288AT, E297K, A376T, T386TI, K390R  
>09316A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFSEVQLGIPHPGGLQKKKSVTILDVGDAFFSIPL
HEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPELVI
CQYVDDLYVASDLEIKQHRTKIEELRQHLWRWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKTLTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKITTESIVIWGKIPKFRLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010