<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y V75M, K219N K103N, G190S   S3C, E6K, V35T, T39A, K43E, E44A, K102KR, K104KR, K122P, D177DN, I178M, T200A, Q207E, A272P, K275R, Q278H, I293V, E297K, K350KR, R356K, G359S, K390R  
>09217A| codons 1-399
PICPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEEAGKISKIGPENPYNTPV
FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKRNRSVTVLDVGDAYFSVPL
DPDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNMVI
YQYVDDLYVSSDLEIGQHRAKIEELREHLWRWGFYTPDNKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLRTGKYAKMRSA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82F, L90M G73S L10V, T12TA, I15IV, L19I, K20KT, R57K, Y59YF, I62V, L63P, A71V, I72IV, V77I, I93L  
>09217A| codons 1-99
PQITLWQRPVVAIKVGGQITEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVKQFD
QVPIEICGHKVVSTVLIGPTPFNIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010