<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y V75L, F77L K103N Y318F V35VL, T39K, K43E, V118VI, K122E, I135M, E138Q, Q174QK, T200TAEK, Q207E, R211RK, Q278H, A288S, I293V, E297A, D324DE, N348NT, M357T, T386I, K390R  
>09065A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICKELEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLLDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSMNNQTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPDIVI
YQYVDDLYVGSDLEIGQHRKKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGTKSLTEVVPLTAEAE
LELAENREILKEPVHGVFYDPSKELIAEIQKQGQGQWTYQIYQEPFKTLKTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54A, V82A, L90M L33F, K43T L10I, V11L, I13V, K14KR, I15V, K20R, E34N, E35D, M36I, R41K, D60E, I62V, L63PQ, I64V, H69HY, A71V, Q92K, I93L  
>09065A| codons 1-99
PQITLWQRPILTVRVGGQLREALLDTGADDTVFNDINLPGKWTPKMIGGIGGFAKVRQYE
QVQVEICGYKVIGTVLVGPTPANIIGRNLMTKLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010