<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70G, L74V, T215Y K219Q K103N, Y181C, G190A K101H E6EK, K11R, K20R, E44D, S68G, K122E, D123E, I135V, I142V, S162Y, I167V, R172RK, Q174R, E194K, G196D, Q207H, R211K, D218E, L228H, A272P, K277R, E297K, I329L, G333E, Y342F, M357V, V365VI, T369A, E370D, A376T, T386P, K390R L210T
>08848A| codons 1-399
PISPIKTVPVRLKPGMDGPRVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV
FAIKKKNGTGWRKVVDFRELNKRTQDFWEVQLGIPHPAGLHKNKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKVLEPFKKRNPDIVI
CQYMDDLYVASDLKIDQHRTKIEELRHHLTKWGFYTPEQKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQEQGQWTYQIFQEPFKNLKTGKYARVRGA
HTNDIKQLADAVQKITTESIVIWGKPPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82VA, L90M G73S L10I, I15V, K20V, K45KR, R57K, L63P, A71I, I72R, V77I, I93L  
>08848A| codons 1-99
PQITLWQRPIVTIKVGGQLVEALLDTGADDTVLEEMNLPGRWKPRIIGGIGGFIKVKQYD
QIPIEICGHKIRSTVLIGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010