<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70E, Y115F, Q151M V75I, F77L, F116Y Y188L   V35I, T39S, V106I, K122E, I135T, Q174K, I178M, G196E, Q207K, R211A, F214L, A272P, K275R, I293V, E297K, K311R, Q334L, Y354F, V365I, T369TA, K390R  
>08757A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICSEMEKEGKISKIGPENPYNTPV
FAIKKKNSTEWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAFYSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKKNPDMVI
YQYMDDLLVGSDLEIEQHRTKIEELRKHLLAWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVVPLTKEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKFARMRGA
HTNDIKQLAEAVQKIATESIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, I84V, L90M K43T, T74P L10I, G16GA, K20R, E35D, M36V, N37E, I62V, L63P, A71V, Q92QK, I93L  
>08757A| codons 1-99
PQITLWQRPIVTIKIAGQLREALLDTGADDTVLEDVELPGRWTPKLIGGIGGFVKVRQYD
QVPIEICGHKVIGPVLVGPTPVNVIGRNLMTKLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010