Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, I84V, L90M | K43T, T74P | L10I, G16GA, K20R, E35D, M36V, N37E, I62V, L63P, A71V, Q92QK, I93L |
| >08757A| codons 1-99 PQITLWQRPIVTIKIAGQLREALLDTGADDTVLEDVELPGRWTPKLIGGIGGFVKVRQYD QVPIEICGHKVIGPVLVGPTPVNVIGRNLMTKLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70E, Y115F, Q151M | V75I, F77L, F116Y | Y188L | V35I, T39S, V106I, K122E, I135T, Q174K, I178M, G196E, Q207K, R211A, F214L, A272P, K275R, I293V, E297K, K311R, Q334L, Y354F, V365I, T369TA, K390R |
| >08757A| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICSEMEKEGKISKIGPENPYNTPV FAIKKKNSTEWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAFYSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKKNPDMVI YQYMDDLLVGSDLEIEQHRTKIEELRKHLLAWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVVPLTKEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKFARMRGA HTNDIKQLAEAVQKIATESIVIWGKTPKFRLPIQKETWEA |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |