<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I50V, I54V, L90M L10FI, V11VI, G73GDNS, L89V K20IMV, E35DN, M36I, R41RK, I62V, L63P, A71V, I85V, Q92K  
>08756A| codons 1-99
PQITLWQRPIITIKIGGQLVEALLDTGADDTVLENINLPGKWKPKMIGGVGGFVKVRQYD
QVPIEICGHKVISTVLVGPTPVNIVGRNVMTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, V75M, M184V, L210W, T215Y F77L, K219R G190A A98G V35VIL, T39A, K43E, E44D, T69TN, V118I, K122E, E203K, Q207E, H208Y, R211K, K223E, L228H, A288T, I293V, E297R, S322T, Q334E, R356K, M357MI, G359S, A376S, T377Q, K390R  
>08756A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICAELEEDGKISKIGPENPYNTPV
FAIKKKDSNKWRKLMDLRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVASDLEIGQHRTKIKELREYLWKWGFYTPDRKHQEEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKTLTEVVPLTREAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKIRSA
HTNDVKQLTEAVQKISQESIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010