Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, V75M, M184V | N348I | L100I | V8I, K122E, D123A, I135T, K166R, K173KE, I178M, E194A, G196GE, T200A, V245E, A272P, K277R, K281R, I293V, E297K, G359S, K390R |
| >08710A| codons 1-399 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKRKDSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGIKKKKSVTVLDVGDAYFSVPL DEAFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFREQNPDMVI YQYVDDLYVGSDLAIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYARMRSA HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | I15V, N37E, L63V, K70R |
| >08710A| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMELPGRWKPKMIGGIGGFIKVRQYD QIVIEICGHRAIGTVLVGPTPVNIIGRSLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |