<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, M184V, T215Y   K101P A98G K43E, E44A, V118I, K122E, A158S, S162N, I178M, G196E, Q197QK, T200TI, Q207D, H208Y, L210Y, K223Q, L283I, A288AT, I293V, F346Y, R356K, M357T, K366R, A400T E203KR
>08709A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLPKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQNSMTKILEPFRKQNPDMVI
YQYVDDLYVGSDLEIEKHRIKIRELRDYLYRWGFYTPDKKHQQEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKTLTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPYKNLKTGKYAKTRGA
HTNDVRQLTEAVQKIATESIVIWGKTPKFKLPIQKETWET

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N N88D I13IV, L19V, N37H, K45R, L63P, H69Q, A71AT, V77I  
>08709A| codons 1-99
PQITLWQRPLVTVKIGGQVKEALLDTGADNTVLEEMHLPGRWKPRMIGGIGGFIKVRQYD
QIPIEICGQKTIGTVLIGPTPVNIIGRDLLTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010