<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54IV, I84V, L90M   L10I, I13IV, K20M, E35D, M36I, N37E, L63P, I64V, Q92QK  
>08700A| codons 1-99
PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEDIELPGRWKPKIIGGIGGFVKVRQYD
QIPVEICGHKAIGTVLVGPTPVNVIGRNLMTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67N, L74LI, L210W, T215TNSY   Y181YC A98AG E44ED, K122KE, T200E, E203EK, E204ED, R211K, L228LF, A272P, T286A, E297K, E328D, Q334E, R358K, V365VI, K366R, A376T, K390R, E399D  
>08700A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVGSDLEIGQHREKIKDLRQHLWKWGFYTPDKKHQKEPPFFWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIADIQKQGEGQWTYQIYQEPFKNLKTGKYARMKGA
HTNDIRQLTEAVQKITTESIVIWGKTPKFRLPIQKETWD

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010