<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, T215Y K219Q, N348NI G190S   V35IM, K49KR, D123E, I135T, E169D, D177E, V189VI, G196E, T200A, D218E, A272P, K277R, E297K, Q334E, P345E, K350R, M357T, K390R, A400S  
>08636A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTELEKEGKISRIGPENPYNTPV
FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPEIVI
YQYMDDLYISSDLEIEQHRAKIEELRQHLLRWGFYTPEQKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEEFKILRTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWES

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82T, I84V L24I L10I, T12S, I13V, K20M, M36V, L63P, A71V, I72V  
>08636A| codons 1-99
PQITLWQRPIVSVKIGGQLMEALIDTGADDTVLEEVNLPGRWKPKIIGGIGGFIKVRQYD
QIPIEICGHKVVGTVLVGPTPTNVIGRNLLTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010