<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I84V   L10V, I13V, K14R, I15V, L19I, K20T, Y59F, I64V, I66F, H69I, T91A, Q92R  
>08631A| codons 1-99
PQITLWQRPVVTVRVGGQITEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQFD
QILVEFCGIKAIGTVLVGPTPVNVIGRNLLARIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, L210W, T215Y N348I L100LI, K101KPQT, K103N   V35I, K43E, E44A, R83K, D121Y, K122E, I135T, S162Y, D177G, H208Y, R211K, L228LR, A272P, R284K, R356K, M357T, K366R, A376S, T377R, K390R  
>08631A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEEAGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKKTQDFWEVQLGIPHPAGITKNKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPGIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYAKTRGA
HTNDVRQLTEAVQKISRESIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010