<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, L74I, M184V, T215F K219Q K103H, Y181C, G190A A98G, V108I P4PS, V21I, V35VI, V60I, V90I, K102R, K122E, S162N, I178IM, E194EG, R211RK, D218E, L228H, V245T, A272S, Q278H, I293V, P294AV, E297A, K311R, D324E, Q334N, E344D, G359GS, T377R, V381I, K390R, E399D  
>08587A| codons 1-400
PISSIETVPVKLKPGMDGPKIKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSDRWRKIVDFRELNKRTQDFWEIQLGIPHPGGLKRHKSVTILDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDMVI
CQYVDDLYVASDLGIGQHRTKIEELRQHLLKWGFFTPEQKHQKEPPFHWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKHLCKLLRGTKALTEVVVLTAEAE
LELAENREILREPVHGVYYDPSKELIAEIQKQGNGQWTYQIYQDPFKNLKTGKYARMRSA
HTNDVKQLTEAVQKIARESIIIWGKTPKFRLPIQKETWDA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54IV, V82A, L90M L10F, F53FL T4TPS, L19V, K20M, M36AV, I62V, L63P, I66F, C67CDGY, H69HQ, A71I, I93L, C95F  
>08587A| codons 1-99
PQISLWQRPFVTIKIGGQVMEALLDTGADDTVLEEVNLPGRWKPKIIGGIGGLVKVRQYD
QVPIEFYGQKIIGTVLVGPTPANIIGRNLMTQLGFTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010