<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R N348I K103N   E6D, V35T, K102Q, K122E, S134SR, S162C, Q174R, G196E, T200I, Q207D, V245K, D250E, K277R, I293V, G333E, P345Q, F346Y, R356RK, D364A, T369TI, T377R  
>08586A| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPRINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKRNPDIVI
YQYMDDLYVGSDLEIEQHRIKIEELRDHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEQYKILKTGKYAKMRGA
HTNAVKQLIEAVQKIARESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   I15V, K20T, E35D, M36I, N37S, R41K, I62V, I64V, V82I, I93L  
>08586A| codons 1-99
PQITLWQRPLVTIKVGGQLTEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYD
QVLVEICGHKAIGTVLVGPTPINIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010