<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV   L10V, I15V, E35D, M36I, I62V, L63A, L89M  
>08472A| codons 1-99
PQITLWQRPVVTIKVGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFVKVRQYD
QVAIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69DN, K70R, M184V K219Q Y188L A98G K20R, A33AG, V60I, V106I, I135V, E203D, R211K, F214FL, L228H, A272PS, T286A, T296S, E297K, I326V, Q334QL, G335GS, G359S, T369TA, A371V, A376S, T377TI, K390R, E399D, A400S  
>08472A| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKGLVEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSITVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLLVGSDLEIGQHRTKIDELRQHLLKWGLTTPDQKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVIPLSKEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGLSQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLAEVVQKISIESIVIWGKTPKFRLPIQKETWDS

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010