<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, L74V, T215F D67K, K219Q K103N, Y181C, G190A K238N K20R, V35VL, K43KN, V60I, K101R, K102Q, K122E, D123N, I135V, D218E, L228H, D237DN, V245VE, I293V, E297R, I329V, A371V, I375IV  
>08457A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICTELENEGKISKIGPENPYNTPI
FAIKKKKSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLRQNKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGFFTPEQKHQKEPPFHWMGYELHPNNWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEVVQKVATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, V82S L24I, L33LF, F53L L10I, E34EQ, K55R, I62V, L63P, I64V, A71V, V77I  
>08457A| codons 1-99
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVFQEMNLPGRWKPKIVGGIGGLVRVRQYD
QVPVEICGHKVIGTVLIGPTPSNIIGRNLLTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010