<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
08036A 08036A U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V, T215F K219E K103NS, Y181YC, G190A K101HQ S48T, V60I, T69N, K122E, S162A, D177E, I178M, D218DE, L228LR, V245T, A272P, I293IV, E297EK, Q334D, M357R, A360T, A371V, K390R, A400T  
>08036A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKITKIGPENPYNTPI
FAIKKKNSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKSKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPEMVI
CQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGFFTPEEKHQKEPPFRWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYARRRGT
HTNDVKQLTEVVQKIATESIVIWGKTPKFRLPIQKETWET

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MIL, I54IV, V82A, L90M G73C L10I, I15V, L19I, K55R, I62V, L63P, I72IV, T74S, I93IL  
>08036A| codons 1-99
PQITLWQRPIVTIKVGGQIKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVRVRQYD
QVPIEICGHKAVCSVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010