<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, L74LI, M184V, L210W, T215Y D67DG, F116FY, K219R G190S V108VI, F227FL E6D, K43E, E44A, V60I, V118I, I142V, K166R, E203K, H208Y, R211D, K223E, L228H, A272P, K277R, A288T, I293V, E297A, I329L, Q334QP, G335GS, F346N, M357T, G359S, T369A  
>07991A| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPI
FAIKKKGSDKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYYSIPL
DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI
YQYVDDLYVSSDLEIGQHRTKIKELRQYLWDWGFYTPDRKHQEEPPLHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKTLTEVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGPSQWTYQIYQEPNKNLKTGKYARTRSA
HTNDVKQLAEAVQKIATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M   L10I, I13V, I15V, K20I, E35D, M36I, N37NS, R41K, I62V, L63P, A71T, T74S  
>07991A| codons 1-99
PQITLWQRPIVTVKVGGQLIEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFVKVRQYD
QVPIEICGHKTIGSVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010