Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | K122E, I142V, V179I, T200A, I202V, R211K, A272S, K277R, T286A, E291D, V292I, I293V, H315Y, D324E, Q334E, M357T, T377L, K390R |
| >07947A| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYMDDLYVGSDLEIGQHRAKVEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVYGVYYDPSKELIAEIQKQGEGQWTYQIYQEPFKNLKTGKYARTRGA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82T, L90M | G73T | L10I, L19I, E35D, N37D, L63P, A71V |
| >07947A| codons 1-99 PQITLWQRPIVTIKIGGQIKEALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFVKVRQYD QIPIEICGHKVITTVLVGPTPTNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |